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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTYH3
All Species:
10.12
Human Site:
S519
Identified Species:
24.73
UniProt:
Q9C0H2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0H2
NP_079526.1
523
57545
S519
T
S
Q
P
R
P
D
S
S
G
S
H
_
_
_
Chimpanzee
Pan troglodytes
XP_001168124
534
58729
R526
S
V
A
D
E
H
L
R
H
Y
G
N
Q
F
P
Rhesus Macaque
Macaca mulatta
XP_001103727
399
44376
Dog
Lupus familis
XP_547008
579
63885
S574
T
S
Q
P
R
P
D
S
S
G
S
G
H
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5F7
524
57695
S519
T
S
Q
P
R
P
D
S
S
G
S
G
H
_
_
Rat
Rattus norvegicus
P0C5X8
450
49014
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513420
642
71454
S520
T
N
Q
P
R
P
D
S
G
T
L
L
R
P
H
Chicken
Gallus gallus
XP_414776
509
56810
A505
T
N
Q
P
R
P
D
A
G
S
V
H
_
_
_
Frog
Xenopus laevis
Q6GPA5
522
58963
A512
S
M
R
A
K
Y
L
A
T
N
R
P
E
T
D
Zebra Danio
Brachydanio rerio
Q32LT7
560
62173
R522
T
S
R
P
D
Q
P
R
P
T
E
S
Q
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.3
74.3
77.5
N.A.
94.6
34.7
N.A.
66.6
72.4
73
66.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
57.4
74.9
79.9
N.A.
96.1
49.7
N.A.
72.7
81.4
82.4
76.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
84.6
N.A.
84.6
0
N.A.
46.6
58.3
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
0
84.6
N.A.
84.6
0
N.A.
53.3
75
33.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
0
20
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
0
50
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
10
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
20
30
10
20
0
0
10
% G
% His:
0
0
0
0
0
10
0
0
10
0
0
20
20
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
20
0
0
0
10
10
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
0
0
0
0
0
0
0
10
0
10
0
10
0
% N
% Pro:
0
0
0
60
0
50
10
0
10
0
0
10
0
10
10
% P
% Gln:
0
0
50
0
0
10
0
0
0
0
0
0
20
0
0
% Q
% Arg:
0
0
20
0
50
0
0
20
0
0
10
0
10
0
0
% R
% Ser:
20
40
0
0
0
0
0
40
30
10
30
10
0
0
0
% S
% Thr:
60
0
0
0
0
0
0
0
10
20
0
0
0
10
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
20
40
40
% _